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L-ARGININE, L-GLUTATHIONE AND N-ACETYL CYSTEINE

Summary:

Maintaining good general health and the proper functioning of male sexual organs including the prostate can be included in the body functions which (NO) assists. Specifically, (NO) helps relax the smooth muscles which control urine flow otherwise obstructed by an enlarged prostate.

One major way which the body utilizes to form (NO) at the right time in the right part of the body is the metabolism of the amino acid, L-arginine. Supplementing the diet with L-arginine provides the extra supply of this source of (NO) at the time and place in the body when it is required.

Once (NO) is formed from L-arginine in the body cells, the (NO) needs to be transported to those parts of the body, such as the smooth muscles, where it can perform the desired action, such as relaxing those smooth muscles. The carrier for (NO) in the body is L-glutathione.

L-Glutathione is a major, on-the-spot antioxidant in the body. When one takes vitamin C or vitamin E, it is so that the antioxidant action of L-glutathione can be repeated over and over. N-acetyl cysteine is a building block from which L-glutathione is made within the liver.

One can see that N-acetyl Cysteine enhances the amount of L-glutathione in the body. In case there is any problem in this transformation, it is well to supplement with some of the straight L-glutathione which will transport (NO) within the body to the places where it will be helpful. As we have said, one of those places is in the prostate where the effects of benign prostate hyperplasia are modified. The extra (NO) needed for men with prostate problems can come from L-arginine metabolism and (NO) transport as provided for in this supplementation.

L-arginine Research:

This amino acid helps to increase the release of nitric oxide, which is important in initiating the erectile process, and increased blood flow to the smooth muscle spongy tissue in the male reproductive organ. This substance can be purchased at any health food store. This is a special formulation high in L-arginine with other components that help to shrink the prostate.

L-arginine Deficiency:

Symptoms of L-arginine deficiency include poor wound healing, hair loss, skin rash, constipation, and fatty liver. L-arginine is considered a semi-essential amino acid.

L-arginine and Nitric Oxide:

L-arginine is a precursor of nitric oxide, which causes blood vessel relaxation. Although there is some evidence that suggests that L-arginine may be useful in the treatment of medical conditions that are improved by vasodilation, such as angina, atherosclerosis, coronary artery disease, erectile dysfunction, heart failure, intermittent claudication / peripheral vascular disease, and vascular headache, more proof is needed. Arginine also stimulates protein synthesis and has been studied for wound healing, bodybuilding, enhancement of sperm production (spermatogenesis), and prevention of wasting in people with critical illness.

It is extremely useful in enhancing the immune system, and it increases the size and activity of the thymus gland, which is responsible for manufacturing T lymphocytes the much talked about T-cells, which assist the immune system. For this reason it might be an important nutrient for people suffering from AIDS and other malignant diseases which suppress the immune system.

In the pancreas it is used to release insulin and in the pituitary gland it is a component of human growth hormone, and is used in sexual stimulants, as people report longer and more intense orgasms when their intake of arginine is increased.

It is also important in liver health and assists in neutralizing ammonia in the liver, while it is also involved in the skin and connective tissue making it important in healing and repair of tissue as well as the formation of collagen and building of new bone and tendons.

L-arginine is found in seminal fluid and L-arginine is used in the treatment of male sexual health and has been used in the treatment of sterility.

It is required in muscle metabolism maintaining the nitrogen balance, and helping with weight control since it facilitates the increase of muscle mass, while reducing body fat.

Dosage

Dosage listed is the Recommended Daily Allowance (RDA), but be aware that this dosage is the minimum that you require per day to ward off serious deficiency of this particular nutrient. In the therapeutic use of this nutrient, the dosage is usually increased considerably.

L-arginine causes retardation of tumors and cancer, aids in leer detoxification, assists in the release of growth hormones and maintenance of a healthy immune system, detoxifies ammonia, increases sperm count in males, and aids in honey disorders and trauma. Scar tissue that forms during wound healing has a high arginine content. This amino acid is needed for protein synthesis and for optimum growth. An increase in muscle mass and a reduction of body fat occurs in the presence of L-arginine. It also helps increase production of collagen, and is good for liver disorders such as cirrhosis of the leer and fatty liver. L-arginine should be avoided if pregnant or lactating.

General Health Information:

The prostate is a male gland that is situated below the bladder and surrounds the urethra like a doughnut. It secretes a milky fluid that lubricates the urethra to prevent infections, and increases sperm motility during ejaculation for better fertilization. Inflammation of the prostate gland is known as prostatitis, and can occur at any age. This inflammation can be caused by bacteria from other parts of the body invading the prostate. This is a different condition than an enlarged prostate. Enlargement of the prostate is an extremely common condition in men, and is known as benign (nonmalignant) prostatic hyperplasia (BPH). Enlargement of the prostate can pinch off the flow of urine causing increased urinary frequency, frequent nighttime urination, and reduced flow of urination. Suffering from BPH does not mean that you have prostate cancer, although the symptoms of prostate cancer can be the same as with BPH. A test for a specific protein level, called a PSA test (prostate-specific antigen), should be performed to rule out cancer.

Most men experience BPH to some degree as they age, because it is caused by the hormonal changes associated with aging. As men age, testosterone levels decrease and estrogen levels increase. There is also an increase in activity of the enzyme 5-alpha-reductase, which converts testosterone to the more potent dihydrotestosterone (DHT). These elevated estrogen levels may inhibit the elimination of excess DHT from the prostate gland. DHT can cause an overproduction of prostate cells resulting in enlargement of the prostate. In addition to the natural processes of aging, certain lifestyle factors also come into play with BPH. Alcohol (especially beer), stress, and toxic contaminants can increase the production of DHT. Avoidance of these precipitating factors may help to reduce the onset and symptoms of BPH.

There are nutritional components to BPH. Zinc, for example, may inhibit the activity of 5-alpha-reductase, the enzyme that converts testosterone to DHT. The herbs saw palmetto and nettle also inhibit 5-alpha-reductase. Another important herb is pygeum with its diuretic and anti-inflammatory activities that may help to reduce nighttime urinary frequency. It is also good to limit caffeine intake because it increases the frequency and urgency to urinate. These nutritional and herbal supplements as part of a healthy lifestyle make for good prostate health.

Nitric Oxide Created In The Body From Ingredients In Complete Prostate Nutrition

Proper balance of nitric oxide (NO) in the body facilitates many desirable functions. Proper functioning of male sexual organs including the prostate can be included in the body functions which (NO) assists. (NO) will help relax the smooth muscles which control urine flow.

One major way which the body utilizes to form (NO) at the right time in the right part of the body is the metabolism of the amino acid, L-arginine. Supplementing the diet with L-arginine provides the extra supply of this source of (NO) at the time and place in the body when it is required.

Once (NO) is formed from L-arginine in the body cells, the (NO) needs to be transported to those parts of the body, such as the smooth muscles, where it can perform the desired action, such as relaxing those smooth muscles. The carrier for (NO) in the body is the ubiquitous tripeptide, L-glutathione. An extra supply of L-glutathione will ensure the transport of (NO) from the site where it is formed from L-arginine.

L-Glutathione is a major, on-the-spot antioxidant in the body. When one takes vitamin C or vitamin E, the antioxidant action of L-glutathione can be repeated over and over. N-acetyl cysteine is a building block from which L-glutathione is made within the liver.

One can see that N-acetyl cysteine enhances the amount of L-glutathione in the body. Supplementation with L-glutathione will transport (NO) within the body to the places where it will be helpful. As we have said, one of those places is in the prostate where the effects of benign prostate hyperplasia are modified. The extra (NO) needed for men with prostate problems can come from L-arginine metabolism and (NO) transport as provided for in this supplementation.

Merrill Andrus, PhD

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